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Symbol Name ID |
Ctnnb1
catenin beta 1 MGI:88276 |
| Darker colors indicate more annotations |
| Human Phenotypes | Dysgerminoma |
Ovarian papillary adenocarcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with CTNNB1 | |||
| colorectal cancer | |||
| ovarian cancer |
| Mouse Phenotypes | abnormal spermatogonia morphology |
squamous metaplasia of preputial gland |
squamous metaplasia of bulbourethral gland |
abnormal seminiferous tubule morphology |
seminiferous tubule degeneration |
decreased testis weight |
testicular atrophy |
increased ovary tumor incidence |
increased granulosa cell tumor incidence |
increased prostate gland adenocarcinoma incidence |
increased prostate intraepithelial neoplasia incidence |
increased testis tumor incidence |
abnormal foreskin morphology |
abnormal external female genitalia morphology |
abnormal external male genitalia morphology |
abnormal sex determination |
male infertility |
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| Availability | Mouse Genotype | |||||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Gli1tm3(cre/ERT2)Alj/Gli1+ (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Nanos3tm2(cre)Ysa/Nanos3+ (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Emx1tm1(cre)Yql/Emx1+ (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Nanos3tm2(cre)Ysa/Nanos3+ (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Gli1tm3(cre/ERT2)Alj/Gli1+ (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Pbsn-cre)4Prb/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(CYP19A1-cre)1Jri/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Nanos3tm2(cre)Ysa/Nanos3+ (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1+ Nanos3tm2(cre)Ysa/Nanos3+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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